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Fertility in Men With CF

The Biology of Male Reproduction and CF

To understand the inner workings of infertility in men with cystic fibrosis, it is helpful to first understand the biology of the male reproductive system. It has three primary parts: the testicles, the epididymis and the vas deferens (see Figure 1).

Figure 1 Figure 2

Sperm (the reproductive cells) are developed in the testicles. The epididymis is a series of tubes that sit behind the testicles where sperm are stored until they are made available at ejaculation. The vas deferens is a long tube that connects the epididymis to the ejaculatory ducts and acts as a canal so that mature sperm can come through the penis during ejaculation (see Figure 2).

Most men with CF (97 to 98%) are infertile because of an absence of the sperm canal, known as congenital bilateral absence of the vas deferens (CBAVD). The sperm never make it into the semen, making it impossible for them to reach and fertilize an egg through intercourse. The absence of sperm in the semen can also contribute to men with CF having thinner ejaculate and lower semen volume.

The Difference Between Infertility and Sterility

This distinction between infertility and sterility is…

5 Best Multivitamins for Men

When you consume the right amount of essential nutrients every day, you'll be surprised at how good you feel. These essential nutrients include vitamins A, C, D, E, K and F, as well as iron, calcium, magnesium and zinc. 

Many people have a difficult time fulfilling all these needs through diet, but there is another, easier way. A multivitamin can go a long way in addressing those nutritional gaps. There are a wide number of multivitamins available on the market, so you have plenty of options to choose from.

Note that dietary supplements are not regulated by the Food and Drug Administration, leading to a consumer market saturated with inadequate options. There's a broad range of multivitamin brands, from affordable to overly expensive. Here is our take on men's multivitamins. 

What essential vitamins and nutrients do men need?

The Academy of Nutrition and Dietetics recommends men who are missing key vitamins from their diets, lack regular physical activity or adequate amounts of sleep take a multivitamin. Men, specifically, require a multivitamin that contains some of the following.

Vitamin A

Found in cantaloupe, carrots, eggs and milk, vitamin A (along with carotenoids, a version of vitamin A found in plant…

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